Organic Solvents and the Kidney
نویسندگان
چکیده
منابع مشابه
Influence of occupational exposure to organic solvents on kidney function.
Exposure to nephrotoxic substances may cause renal tubular and glomerular dysfunction. The aim of the paper was to evaluate, based on literature reports, whether occupational exposure to organic solvents entails a risk of renal dysfunction. The results of the studies performed over the last twenty years are contradictory. In workers occupationally exposed to organic solvents, tubular, glomerula...
متن کاملIndustrial solvents and kidney disease.
Scientific literature addressing the association of industrial exposures to solvents with glomerular kidney disease is reviewed. The role of the practicing physician in taking an occupational history of exposures to solvents in every case of glomerulonephritis is emphasized. Based on case studies and epidemiologic findings, it is highly probable that exposures to industrial solvents should be c...
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Organic solvents are commonly used in the pharmaceutical industry as reaction media, in separation and purification of synthesis products and also for cleaning of equipment. This paper presents some aspects of organic solvents utilization in an active pharmaceutical ingredient and a drug product manufacturing process. As residual solvents are not desirable substances in a final product, differe...
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Solubility data of solid in aqueous and different organic solvents are very important physicochemical properties considered in the design of the industrial processes and the theoretical studies. In this study, experimental solubility data of 666 pharmaceutical compounds in water and 712 pharmaceutical compounds in organic solvents were collected from different sources. Three different artificia...
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The nervous system is main target of the toxic action of most of organic solvents. There is little doubt that occupational solvent exposure may result in persisting neurobehavioural disturbances--the organic solvent syndrome. Recently, the solvents are quoted among possible causes of the abnormal condition referred to as multiple chemical sensitivity (MCS), and which is characterized by a psych...
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ژورنال
عنوان ژورنال: Journal of Occupational Health
سال: 1996
ISSN: 1341-9145,1348-9585
DOI: 10.1539/joh.38.162